This study is testing whether an investigational treatment called depemokimab, added to regular COPD treatment, can help reduce COPD flare-ups and is safe for people with moderate to severe COPD.
Taking part is your choice. You can leave the study at any time.
Condition
Chronic Obstructive Pulmonary Disease (COPD)
Who it's for
40–80 years
Visits
Not reported
Time commitment
24 months
Study format
Randomized, double-blind, placebo-controlled study.
Study treatment
Provided, free to you
Compensation
Not reported
Your privacy
Kept private and secure
Eligibility
If you have been diagnosed with this condition, you may be eligible to take part. Here is a simple guide to who can join.
These are general guidelines. The study team confirms who can join after a short, friendly check.
The challenge today
People with moderate to severe COPD often keep having flare-ups even while using their regular inhalers, and each flare-up can further damage the lungs and lower quality of life.
What researchers hope to learn
Whether adding Depemokimab, an investigational add-on medicine, to standard inhaler treatment can reduce how often flare-ups happen in adults with COPD who have signs of a specific type of airway inflammation.
How this study treatment may help
If effective, Depemokimab may lower the number and severity of flare-ups over time, on top of the inhalers a participant is already using.
Checks confirm you meet the study's health criteria
Starting point measurements are recorded before treatment begins
You continue your usual inhalers, with the study medicine or placebo added
A final check-in after treatment ends
1.Learn about the study
Read through what's involved and ask any questions
2.Screening visit
The study team checks your health history and current COPD status
3.Find out if you qualify
Based on your seizure (COPD, not seizures) based on your lung function and exacerbation history
4.Start treatment
Begin receiving the study medicine alongside your usual inhalers
5.Regular check-ins
The study team monitors your symptoms and any flare-ups
6.Study completion
A final visit wraps up your participation
For check-ups and study medicine administration
The study medicine is an add-on, not a replacement
Let the study team know if your symptoms worsen
Brief check-ins about how you're feeling
The study team will walk you through every possible before you decide. You will have time to ask questions.
Not reported
No. You do not need insurance to take part, and study-related care is provided at no cost to you.
Often yes, but it depends on the study. Share your full medication list with the study team and they will guide you.
Yes. Taking part is your choice, and you can stop at any time for any reason, without affecting your regular care.
You can call or email the study team any time. There is no such thing as a question that is too small.
Yes. Your information is kept private and secure, and only approved people can see your study data.
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Chronic Obstructive Pulmonary Disease (COPD) eligibility
Answer a few simple questions about your COPD, breathing treatments, and health history to see if you may be a potential match for this research study.